Wasps Club Captain Joe Launchbury has been named among the replacements for England’s crucial Guinness Six Nations clash against Scotland at Murrayfield on Saturday (kick-off 4.45pm, live on BBC).
The Wasps star is in line to make his 63rd appearance for the Red Rose.
England Head Coach Eddie Jones has named Mako Vunipola, Jamie George and Kyle Sinckler in the front-row with George Kruis and Maro Itoje selected in the second-row.
Lewis Ludlam is named at blindside-flanker with Sam Underhill at openside and Tom Curry at number-eight.
Willi Heinz starts at scrum-half with Ben Youngs named as a finisher. George Ford and captain Owen Farrell will play fly-half and inside-centre with Jonathan Joseph named at outside-centre.
George Furbank, who made his England debut last weekend, is selected at full-back with Elliot Daly and Jonny May on the wings.
Uncapped players Tom Dunn and Ben Earl are included as finishers with Launchbury returning to the matchday 23 after recovering from injury.
Jones said: “Preparation this week has been great. We have sought to address the issues from the France game and have had a really good and sharp preparation for Scotland.
“Scotland are a dangerous side. They like to play with a lot of width and with a lot of flow and tempo in their game. We want to make sure we dominate the gain line.
“Their win record against England at Murrayfield is substantially higher than their overall record against us, so we have to recognise they are a dangerous beast and we have to be at our best to beat them.”
Dunn was recalled back into the squad after Luke Cowan-Dickie left camp this morning to be with his partner who has gone into labour.
15 George Furbank (Northampton Saints, 1 cap)
14 Jonny May (Leicester Tigers, 53 caps)
13 Jonathan Joseph (Bath Rugby, 48 caps)
12 Owen Farrell (Saracens, 80 caps) C
11 Elliot Daly (Saracens, 40 caps)
10 George Ford (Leicester Tigers, 66 caps)
9 Willi Heinz (Gloucester Rugby, 10 caps)
1 Mako Vunipola (Saracens, 58 caps)
2 Jamie George (Saracens, 46 caps)
3 Kyle Sinckler (Harlequins, 32 caps)
4 Maro Itoje (Saracens, 35 caps)
5 George Kruis (Saracens, 42 caps)
6 Lewis Ludlam (Northampton Saints, 7 caps)
7 Sam Underhill (Bath Rugby, 16 caps)
8 Tom Curry (Sale Sharks, 20 caps)
16 Tom Dunn (Bath Rugby, uncapped)
17 Ellis Genge (Leicester Tigers, 15 caps)
18 Will Stuart (Bath Rugby, 1 cap)
19 Joe Launchbury (Wasps, 62 caps)
20 Courtney Lawes (Northampton Saints, 82 caps)
21 Ben Earl (Saracens, uncapped)
22 Ben Youngs (Leicester Tigers, 96 caps)
23 Ollie Devoto (Exeter Chiefs, 2 caps)
Matteo Minozzi has been named on the left wing for Italy as they prepare to take on France at Stade de France on Sunday (kick-off 3pm GMT).
The Wasps flyer was impressive last weekend despite his side's 42-0 loss to Wales.
15 Jayden HAYWARD (Benetton Rugby, 24 caps)
14 Mattia BELLINI (Zebre Rugby Club, 23 caps)
13 Luca MORISI (Benetton Rugby, 30 caps)*
12 Carlo CANNA (Zebre Rugby Club, 40 caps)
11 Matteo MINOZZI (Wasps Rugby, 17 caps)*
10 Tommaso ALLAN (Benetton Rugby, 55 caps)
9 Callum BRALEY (Gloucester Rugby, 6 caps)
8 Abraham STEYN (Benetton Rugby, 37 caps)
7 Sebastian NEGRI (Benetton Rugby, 23 caps)
6 Jake POLLEDRI (Gloucester Rugby, 14 caps)
5 Niccolò CANNONE (Argos Petrarca Rugby/Benetton Rugby,1 cap)*
4 Alessandro ZANNI (Benetton Rugby, 118 caps)
3 Giosuè ZILOCCHI (Zebre Rugby Club, 3 caps)*
2 Luca BIGI (Zebre Rugby Club, 25 caps) - capitano
1 Andrea LOVOTTI (Zebre Rugby Club, 41 caps)*
16 Federico ZANI (Benetton Rugby 14 caps)
17 Danilo FISCHETTI (Zebre Rugby Club, 1 cap)*
18 Marco RICCIONI (Benetton Rugby, 8 caps)*
19 Dean BUDD (Benetton Rugby, 27 caps)
20 Federico RUZZA (Benetton Rugby, 18 caps)*
21 Giovanni LICATA (Zebre Rugby Club, 9 caps)*
22 Guglielmo PALAZZANI (Zebre Rugby Club, 37 caps)
23 Giulio BISEGNI (Zebre Rugby Club, 14 caps)