England select Wasps skipper to start against Wales
Joe Launchbury has retained his place in Eddie Jones' starting line-up for this weekend's second round of Nat West Six Nations action.
The Wasps lock moves within one cap of completing a half-century of international appearances when he lines up against Wales at Twickenham (4.45pm kick off).
England make two changes to the side that beat Italy 46-15 on Sunday in Rome.
Harlequins' Danny Care starts at scrum-half and in the process moves past 2003 Rugby World Cup winner Matt Dawson as his country's most-capped No.9.
Bath's Jonathan Joseph comes in for Ben Te’o (Worcester Warriors) at outside centre.
One personnel change in the 23 sees Saracens' Richard Wigglesworth join the bench as a replacement for the injured Ben Youngs.
England's head coach complemented Care on his achievement, and said his team is well set for the challenge provided by Wales, who comfortably beat Scotland in Cardiff last Saturday.
“Danny Care very much deserves the honour of being the most capped England scrum half and I am sure he’ll make the most of his opportunity on Saturday,” Jones said.
“The team is hugely excited about playing in front of 82,000 fans at Twickenham and we’ll be well prepared and ready to go out there and beat Wales on Saturday.
“We want to make sure our set piece is dominant, our defence is ferocious and that we are at our best this weekend."
15 Mike Brown (Harlequins 65 caps)
14 Anthony Watson (Bath Rugby 29 caps)
13 Jonathan Joseph (Bath Rugby 36 caps)
12 Owen Farrell (Saracens 54 caps)
11 Jonny May (Leicester Tigers 30 caps)
10 George Ford (Leicester Tigers 41 caps)
9 Danny Care (Harlequins 77 caps)
1 Mako Vunipola (Saracens 45 caps)
2 Dylan Hartley (Northampton Saints 90 caps)
3 Dan Cole (Leicester Tigers 78 caps)
4 Joe Launchbury (Wasps 48 caps)
5 Maro Itoje (Saracens 15 caps)
6 Courtney Lawes (Northampton Saints 62 caps)
7 Chris Robshaw (Harlequins 60 caps)
8 Sam Simmonds (Exeter Chiefs 4 caps)
16 Jamie George (Saracens 21 caps)
17 Alec Hepburn (Exeter Chiefs 1 cap)
18 Harry Williams (Exeter Chiefs 6 caps)
19 George Kruis (Saracens 22 caps)
20 Sam Underhill (Bath Rugby 4 caps)
21 Richard Wigglesworth (Saracens 27 caps)
22 Ben Te’o (Worcester Warriors 9 caps)
23 Jack Nowell (Exeter Chiefs 24 caps)
Tickets for the Aviva Premiership visit of champions Exeter Chiefs on February 18 and London Irish on March 4 are available at www.wasps.co.uk/tickets
on 02476 786411 or in person from the Ricoh Arena ticket office.