The Game Changer rewards the player responsible for the most effective single performance each month, according to Opta’s Performance Statistics.
Vunipola registered 11 carries, 11 tackles and beat five defenders in open play whilst covering 111 metres when Wasps took on Sale, helping his side to record a 25-18 victory.
Vunipola is the fourth player this season to receive the Gatorade Game Changer Award.
Each of the Game Changer winners will be competing for the Game Changer of the Season Award in May. Last season’s Award was won by Exeter Chiefs’ Gonzalo Camacho.
On being presented the Award by Gatorade, an Official Performance Partner to Premiership Rugby, Vunipola said: “The season so far has been good for us, everyone is in high spirits and looking forward to a strong 2013. It is always great to have performances recognised with awards such as the Game Changer.”