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Heineken Cup semi-finalists Gloucester were put to the sword by Wasps, who took full advantage of a poor performance by the home side.
The cherry and whites started well enough, but their game gradually disintegrated with the crucial phase coming early in the second half when they conceded 17 points in an eight minute spell of Wasps dominance.
Gloucester had started with a series of driving runs which brought them a second-minute penalty chance. But fly-half Byron Hayward pulled the kick wide.
Early exchanges were hotly contested, with referee Robin Goodliffe handing out a series of penalties and lectures. One of these was to Wasps captain Lawrence Dallaglio.
He was in evidence moments later with a 40-yard solo dash which set up a penalty which Kenny Logan put over.
Gloucester's forwards were strong in tight and loose play but another Logan penalty was followed by a superb dash from Dallaglio.
He broke from just inside his own half only to be brought down by a superb Chris Catling tackle five yards out.
Flanker Paul Volley was first to the loose ball and drove over for a try which Logan failed to convert.
Gloucester were finally rewarded when another forward drive ended with a successful penalty by Hayward just before half-time.
A trio of sin-bin decisions at the start of the second half saw Dallaglio and his back-row partner Volley, as well as Hayward, going off.
Gloucester still could not make any impression and then their defence went to pieces as Joe Worsley and then Rob Henderson went over for tries, with Logan converting both.
Logan then added a penalty to complete the scoring.
Gloucester tightened it up towards the end, but their midfield play, handling and ball retention were often lacking.
Wasps were tenacious in their tackling, especially in the back row where Volley was in great form, and Dallaglio was impressive in all phases.
GLOUCESTER : 3
Tries: Volley, Henderson 2, Worsley
Cons: Logan 3
Pens: Logan 3